 Clifford
Pohl, Ph.D.
Associate Professor
Department of Physical Therapy
Degrees:
Ph.D., University of Rochester School of Medicine & Dentistry
Courses Taught:
HLTSC 330/480/580, Physiology I
HLTSC 331/481/581, Physiology II
REHSC 635, Histology
Areas of Academic Specialty:
Physiology
Histology
Research Area:
Reproductive Neuroendocrinology
Continuing Education:
Postdoctoral Fellowship in Neuroendocrinology, Department of Physiology, University of Pittsburgh School of Medicine 1/1/79 - 6/30/82
Recombinant DNA Methodology Course, Center for Advanced Training in Cell and Molecular Biology, Catholic University of America, 5/25/87 - 5/29/87
Grants:
(most recent 5)
Center for Research in Reproductive Physiology, Principal Investigator of Assay Core, National Institute of Child Health and Human Development, Grant No. P30 HD08610, Core C, $946,495 (Assay Core direct costs), 7/1/87 - 3/31/00
PACAP and Gonadotropin, Co-Investigator, National Institute of Child Health and Human Development, Grant No. 1R01 HD36034, $576,172 (direct costs), 4/1/99 - 3/31/02
Specialized Cooperative Center for Reproduction Research: Physiology and Pathophysiology of the Primate Gonad, Principal Investigator of Assay Core, National Institute of Child Health and Human Development, Grant No. U54 HD08610, Core C, $371,974 (Assay Core direct costs), 4/1/00 - 3/31/11
Establishing a Histology/Immunocytochemistry Lab for Basic Science Research in the Rangos School of Health Sciences, Co-Principal Investigator, Rangos School of Health Sciences Faculty Practice Plan,
$4979 (direct costs), 5/21/03 - 5/20/04
Programming of the Primate Male Reproductive System by Estrogen In Utero: Impact on Fertility in Adulthood, Co-Investigator, National Institute of Child Health and Human Development, Grant No. 2U54 HD036207, $375,620 (direct costs), 4/1/04 - 3/31/09
Publications:
(most recent 5)
Ramaswamy S, Marshall GR, Pohl CR, Friedman RL, Plant TM. 2003.
Inhibitory and stimulatory regulation of testicular inhibin B secretion by luteinizing hormone and follicle-stimulating hormone, respectively, in the rhesus monkey (Macaca mulatta). Endocrinology 144:1175-1185.
Ramaswamy S, Pohl CR, Marshall GR, Plant TM. 2004. A switch from continuous to episodic testicular testosterone release in response to pulsatile LH stimulation in juvenile rhesus monkeys (Macaca mulatta). J Endocrinol 183:61-68.
Mann DR, Bhat GK, Stah CD, Pohl CR, Plant TM. 2006. Induction of a hypothyroid state during juvenile development delays pubertal reactivation of the neuroendocrine system governing luteinising hormone secretion in the male rhesus monkey (Macaca mulatta). J Neuroendocrinol 18:662-671.
Zeleznik AJ, Pohl CR. 2006. Control of follicular development, corpus luteum function, the maternal recognition of pregnancy, and the neuroendocrine regulation of the menstrual cycle in higher primates. In: Neill JD (ed), Knobil and Neill's Physiology of Reproduction, Third Edition, Volume 2. Elsevier, St. Louis, MO, pp. 2449-2510.
Ramaswamy S, Seminara SB, Pohl CR, DiPietra MJ, Crowley WF Jr, Plant TM. 2007. Effect of continuous intravenous administration of human metastin 45-54 on the neuroendocrine activity of the hypothalamic-pituitary-testicular axis in the adult male rhesus monkey (Macaca mulatta). Endocrinology 148:3364-3370.
Professional Presentations:
(most recent 5)
Suter K, Pohl CR, Plant TM. In the monkey, the waning of the prepubertal restraint on the hypophysiotropic drive to the pituitary-testicular axis is mediated, in part, by an acceleration of the GnRH pulse generator. 77th Annual Meeting of the Endocrine Society, Washington, D.C., 1995.
Pohl CR, Plant TM, Ishwad PC, Winters SJ. A comparative study of the inhibitory action of follistatin on FSH secretion in the rat and rhesus monkey. 77th Annual Meeting of the Endocrine Society, Washington, D.C., 1995.
Bergman I, Burckart GJ, Pohl CR, Venkataramanan R, Barmada MB , Griffin JA, Cheung NKV. Pharmacokinetics of intrathecal administration of an antiganglioside antibody in nude rats with meningeal xenografts. International Symposium on Monoclonal Antibodies and Cancer Therapy, New York, NY, 1995.
Ramaswamy S, Pohl CR, Ishwad PC, Winters SJ, Plant TM. Studies of the dynamics of recombinant human inhibin A suppression of FSH secretion in the adult male rhesus monkey (Macaca mulatta). 79th Annual Meeting of the Endocrine Society, Minneapolis, MN, 1997.
Ramaswamy S, Marshall GR, McNeilly AS, Friedman RL, Pohl CR, Plant TM. Evidence for the view that testosterone (T) plays an inhibitory role in the regulation of testicular inhibin B subunit gene expression and inhibin B secretion. International Workshop on Inhibins, Activins, Follistatins. Melbourne, Australia, 2000.
Awards and Accomplishments:
Faculty Excellence Award for Scholarship, John G. Rangos, Sr. School of Health Sciences, 5/7/99
Faculty Excellence Award for University Service, John G. Rangos, Sr. School of Health Sciences, 5/5/00
Presidential Award for Faculty Excellence in University Service, Duquesne University, 5/5/00
Professional Narrative:
Following a brief career in respiratory therapy, Dr. Pohl earned his Ph.D. (1979) in the Department of Anatomy at the University of Rochester School of Medicine & Dentistry, Rochester, New York. He next served for three years as a postdoctoral fellow of neuroendocrinology in the Department of Physiology, University of Pittsburgh School of Medicine, later obtaining an appointment in that department as a research assistant professor. In 1992 he joined the Department of Physical Therapy, Duquesne University, where he teaches physiology and continues his scientific research in the field of reproductive neuroendocrinology. His research interests are focused on the neurohormonal signals and mechanisms used by the hypothalamus for initiating puberty, sustaining menstrual cycles, and generally driving hormonal systems that utilize biological clocks and pacemakers. He is also the Director of the Assay Core Lab of the Center for Research in Reproductive Physiology, an NIH-funded research center that includes scientists from several institutions in the Pittsburgh area. Dr. Pohl's research program has been continuously funded by the NIH since 1984.
Dr. Pohl serves on numerous committees of Duquesne University and the Rangos School of Health Sciences. He has received the Rangos School of Health Sciences awards for Faculty Excellence in Scholarship and in Service, and the Presidential Award for Faculty Excellence in University Service.
Phone: 412.396.5546
E-mail: pohl@duq.edu
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